Welcome to Four Seasons Hotel San Francisco. In the Yerba Buena cultural district, two blocks from Union Square, the Financial District, the Moscone Convention Center and the Museum of Modern Art, Four Seasons creates a distinctive luxury experience with heart-of-the-city access to all that San Francisco offers. The Hotel’s 277 guest rooms, including 46 suites, are generously sized – the largest in the city – and exude a warm residential feel. The building features floor-to-ceiling windows that showcase stunning views of the city or Yerba Buena Gardens and San Francisco Bay.